Search Results
Overview
| Uniprot ID | K9IVW4 |
|---|---|
| Protein Name | Myotrophin |
| Gene Name | MTPN |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 24 | EVKDYVAKGEDVNRT |
| 90 | CVKLLLSKGADKTVK |
| 97 | KGADKTVKGPDGLTA |
Function
Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer
Protein Sequence
10
MCDKEFMWAL
20
KNGDLDEVKD
30
YVAKGEDVNR
40
TLEGGRKPLH
50
YAADCGQLEI
60
LEFLLLKGAD
70
INAPDKHHIT
80
PLLSAVYEGH
90
VSCVKLLLSK
100
GADKTVKGPD
110
GLTAFEATDN
QAIKALLQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Biological Process | GO:0010613 | positive regulation of cardiac muscle hypertrophy |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.