Search Results
Overview
| Uniprot ID | K9J4U3 |
|---|---|
| Protein Name | - |
| Gene Name | ATP6V1E1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 107 | QRLGKVVKDTTRYQV |
| 138 | RMIVRCRKQDFPLVK |
| 150 | LVKAAVQKAIPVYKI |
| 156 | QKAIPVYKIATKRDV |
| 191 | YNGDRKIKVSNTLES |
| 42 | EEEFNIEKGRLVQTQ |
| 62 | EYYEKKEKQIEQQKK |
Function
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment
Protein Sequence
10
MALSDADVQK
20
QIKHMMAFIE
30
QEANEKAEEI
40
DAKAEEEFNI
50
EKGRLVQTQR
60
LKIMEYYEKK
70
EKQIEQQKKI
80
QMSNLMNQAR
90
LKVLRARDDL
100
ITDLLNEAKQ
110
RLGKVVKDTT
120
RYQVLLDGLV
130
LQGLYQLLEP
140
RMIVRCRKQD
150
FPLVKAAVQK
160
AIPVYKIATK
170
RDVDVQIDQE
180
AYLPEEIAGG
190
VEIYNGDRKI
200
KVSNTLESRL
210
DLIAQQMMPE
220
VRGALFGANA
NRKFLD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016324 | apical plasma membrane |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005768 | endosome |
| Cellular Component | GO:0005902 | microvillus |
| Cellular Component | GO:0098793 | presynapse |
| Cellular Component | GO:0033178 | proton-transporting two-sector ATPase complex, catalytic domain |
| Molecular Function | GO:0046961 | proton-transporting ATPase activity, rotational mechanism |
| Biological Process | GO:0097401 | synaptic vesicle lumen acidification |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.