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Overview

Uniprot IDM0R4P2
Protein NameElongation factor Ts, mitochondrial
Gene NameTsfm
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
64 RSLRFFPVACTGRSA
65 SLRFFPVACTGRSAR
75 GRSARAVLLQPSQPW
83 LQPSQPWHTLHAGPS
87 QPWHTLHAGPSLSSS

Function

Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Participates in mitochondrial translation

Protein Sequence

10 MKQAKETITL 20 PLPPRSASGS 30 VLAPSVLGSV 40 LALAPRRRLA 50 SCLCAVTGRG 60 TGMSLLRSLR 70 FFPVACTGRS 80 ARAVLLQPSQ 90 PWHTLHAGPS 100 LSSSASSKEL 110 LMKLRRTTGY 120 SFVNCKKALE 130 TCGGDLKQAE 140 AWLHKQAQKE 150 GWSKAAKLHG 160 RKTKEGLIGL 170 LQEENTAVLV 180 EVNCETDFVS 190 RNVKFQQLVQ 200 QVALGTMAHC 210 QNLTDQLSTY 220 SKGFLNSSEL 230 SELAAGPDGE 240 GSLKDQLALA 250 IGTLGENMSL 260 KRAAWVKVPS 270 GFYVGSYVHG 280 EMQSPSLQNL 290 VLGKYGALVI 300 CQTPEQITNL 310 EEVGRRLGQH 320 VVGMAPLSVG 330 SLDDEPGGET 340 ETRMLPQPYL 350 LDPSITLGQY 360 VQPQGVTVVD 370 FVRFECGEGV F

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005739 mitochondrion
Molecular Function GO:0003746 translation elongation factor activity

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.