Search Results
Overview
| Uniprot ID | M0R8K2 |
|---|---|
| Protein Name | Small nuclear ribonucleoprotein Sm D2 |
| Gene Name | Snrpd2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 8 | MSLLNKPKSEMTPEE |
Function
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs
Protein Sequence
10
MSLLNKPKSE
20
MTPEELQKRE
30
EEEFNTGPLS
40
VLTQSIKNNT
50
QVLINCRNNK
60
KLLGRVKAFD
70
RHCNMVLENV
80
KEIWTEVPKS
90
GKGKKKSKPV
100
NKDRYISKMF
110
LRGNSVIVVL
RNPLIAGK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0071013 | catalytic step 2 spliceosome |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0034715 | pICln-Sm protein complex |
| Cellular Component | GO:0071011 | precatalytic spliceosome |
| Cellular Component | GO:0005685 | U1 snRNP |
| Cellular Component | GO:0005689 | U12-type spliceosomal complex |
| Cellular Component | GO:0005686 | U2 snRNP |
| Cellular Component | GO:0046540 | U4/U6 x U5 tri-snRNP complex |
| Cellular Component | GO:0005682 | U5 snRNP |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0000387 | spliceosomal snRNP assembly |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.