Search Results
Overview
| Uniprot ID | M0R907 |
|---|---|
| Protein Name | Small nuclear ribonucleoprotein Sm D3 |
| Gene Name | Snrpd3 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 84 | LKNAPMLKSMKNKNQ |
Function
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing
Protein Sequence
10
MSIGVPIKVL
20
HEAEGHIVTC
30
ETNTGEVYRG
40
KLIEAEDNMN
50
CQMSNITVTY
60
RDGRVAQLEQ
70
VYIRGSKIRF
80
LILPDMLKNA
90
PMLKSMKNKN
100
QGSGAGRGKA
110
AILKAQVAAR
120
GRGRGMGRGN
IFQKRR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0071013 | catalytic step 2 spliceosome |
| Cellular Component | GO:0000243 | commitment complex |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0071011 | precatalytic spliceosome |
| Cellular Component | GO:0034719 | SMN-Sm protein complex |
| Cellular Component | GO:0097526 | spliceosomal tri-snRNP complex |
| Cellular Component | GO:0005685 | U1 snRNP |
| Cellular Component | GO:0005686 | U2 snRNP |
| Cellular Component | GO:0005687 | U4 snRNP |
| Cellular Component | GO:0005682 | U5 snRNP |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0000387 | spliceosomal snRNP assembly |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.