Search Results

Overview

Uniprot IDM0RAX2
Protein NameNADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
Gene NameNdufs6
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
102 INLDKETKTGTCGYC
99 KVYINLDKETKTGTC

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Protein Sequence

10 IFWFLPPCLF 20 LLSLSTHPFS 30 FSPTLSCPRG 40 DSAGQILGVY 50 DEKDYRRIRF 60 VDRQKEVNEN 70 FAIDLIAQQP 80 VNEVDHRIIA 90 CDGGGGALGH 100 PKVYINLDKE 110 TKTGTCGYCG LQFKQQHH

Gene Ontology

Classification GO ID Description
Biological Process GO:0006120 mitochondrial electron transport, NADH to ubiquinone
Biological Process GO:0032981 mitochondrial respiratory chain complex I assembly
Biological Process GO:0007005 mitochondrion organization
Biological Process GO:0035264 multicellular organism growth
Biological Process GO:0006936 muscle contraction
Biological Process GO:0072593 reactive oxygen species metabolic process
Biological Process GO:0051881 regulation of mitochondrial membrane potential
Biological Process GO:0061458 reproductive system development
Biological Process GO:0022904 respiratory electron transport chain
Biological Process GO:0017145 stem cell division
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0045271 respiratory chain complex I
Biological Process GO:0090398 cellular senescence
Biological Process GO:0072359 circulatory system development
Biological Process GO:0030330 DNA damage response, signal transduction by p53 class mediator
Biological Process GO:0006631 fatty acid metabolic process
Biological Process GO:0010467 gene expression
Biological Process GO:0001822 kidney development
Biological Process GO:0072497 mesenchymal stem cell differentiation
Biological Process GO:0097168 mesenchymal stem cell proliferation

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.