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Overview

Uniprot IDM0RB65
Protein NameSmall ribosomal subunit protein uS4
Gene NameLOC120097492
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
11 ARSWVCRKTYVTPRR

Function

Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome

Protein Sequence

10 MPVARSWVCR 20 KTYVTPRRPF 30 EKSRLDQELK 40 LIGEYGLRNK 50 REVWRVKFTL 60 AKIRKLLTLD 70 EKDPRCLFEG 80 NALLNRLVQI 90 GVLDEGKMKL 100 DFILGLKIED 110 FLERRLQTQV 120 FKLGLAKSIH 130 HARVLIRQRH 140 IRVLKQVVNI 150 PSFIVRLDSQ 160 KHIDFSLRSP 170 YGGGRPGRVK 180 RKNAKKGQGG 190 AGAGDDEEED

Gene Ontology

Classification GO ID Description
Cellular Component GO:0022627 cytosolic small ribosomal subunit
Cellular Component GO:0005730 nucleolus
Molecular Function GO:0019843 rRNA binding
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:0042274 ribosomal small subunit biogenesis
Biological Process GO:0006412 translation

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.