Search Results
Overview
| Uniprot ID | M0RBK1 |
|---|---|
| Protein Name | ribose-phosphate diphosphokinase |
| Gene Name | Prps1l1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 212 | MVLVGDVKERVAILV |
Function
Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis
Protein Sequence
10
MPNIKIFSGS
20
SHQDLSQKIT
30
ERLGLELGKV
40
VTKKFSNQET
50
CVEIGESVRG
60
EDVYIVQSGC
70
GEINDSLMEL
80
LIMINACKIA
90
SASRVTAVIP
100
CFPYARQDKK
110
DKSRAPMSAK
120
LIANMLSIAG
130
ADHIITMDLH
140
ASQIQGFFDI
150
PVDNLYAEPA
160
VLKWIKENIS
170
DWRNCTIVSP
180
DAGGAKRVTS
190
IADHLNVDFA
200
LIHKERKKAN
210
EVDRMVLVGD
220
VKERVAILVD
230
DMADTCGTIC
240
YAADKLLSEG
250
ATRVYAILTH
260
GIFSGPAIAR
270
INGACFEAVV
280
VTNTIPQEDK
290
MKQCSKIQVI
300
DISMILAEAI
310
RRTHNGESVS
YLFSHVPL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0002189 | ribose phosphate diphosphokinase complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016301 | kinase activity |
| Molecular Function | GO:0000287 | magnesium ion binding |
| Molecular Function | GO:0004749 | ribose phosphate diphosphokinase activity |
| Biological Process | GO:0006015 | 5-phosphoribose 1-diphosphate biosynthetic process |
| Biological Process | GO:0008584 | male gonad development |
| Biological Process | GO:0006164 | purine nucleotide biosynthetic process |
| Biological Process | GO:0009156 | ribonucleoside monophosphate biosynthetic process |
Reference
[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.