Search Results

Overview

Uniprot IDM0RC65
Protein Name-
Gene NameCfl2
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
19 IKVFNDMKVRKSSTQ
22 FNDMKVRKSSTQEEI

Function

No function data available.

Protein Sequence

10 MASGVTVNDE 20 VIKVFNDMKV 30 RKSSTQEEIK 40 KRKKAVLFCL 50 SDDKRQIIVE 60 EAKQILVGDI 70 GDTVEDPYTS 80 FVKLLPLNDC 90 RYALYDATYE 100 TKESKKEDLV 110 FIFWAPESAP 120 LKSKMIYASS 130 KDAIKKKFTG 140 IKHEWQVNGL 150 DDIKDRSTLG 160 EKLGGSVVVS LEGKPL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0015629 actin cytoskeleton
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0031674 I band
Cellular Component GO:0030018 Z disc
Molecular Function GO:0051015 actin filament binding
Biological Process GO:0030042 actin filament depolymerization
Biological Process GO:0030043 actin filament fragmentation
Biological Process GO:0007015 actin filament organization
Biological Process GO:0051014 actin filament severing
Biological Process GO:0046716 muscle cell cellular homeostasis
Biological Process GO:0030836 positive regulation of actin filament depolymerization
Biological Process GO:0045214 sarcomere organization
Biological Process GO:0007519 skeletal muscle tissue development

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.

[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.