Search Results
Overview
| Uniprot ID | M0RDJ4 |
|---|---|
| Protein Name | Glia maturation factor |
| Gene Name | Gmfb |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 24 | LRKFRFRKETHNAAI |
Function
This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells
Protein Sequence
10
SESLVVCDVA
20
EDLVEKLRKF
30
RFRKETHNAA
40
IIMKIDKDKR
50
LVVLDEELEV
60
CSFRFFNLRK
70
TFIVYSYKYQ
80
HDDGRVSYPL
90
CFIFSSPLGC
100
KPEQQMMYAG
110
SKNKLVQTAE
120
LTKVFEIRNT
130
EDLTEEWLRE
KLGFFH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0071933 | Arp2/3 complex binding |
| Molecular Function | GO:0008083 | growth factor activity |
| Biological Process | GO:0071846 | actin filament debranching |
Reference
[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.
[2] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.