Search Results
Overview
| Uniprot ID | M3TYC1 |
|---|---|
| Protein Name | Eukaryotic translation initiation factor 3 subunit B |
| Gene Name | EIF3B |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 186 | KIFSKFGKITNDFYP |
| 224 | VKNADGYKLDKQHTF |
| 227 | ADGYKLDKQHTFRVN |
| 315 | TYVRWSPKGTYLATF |
| 406 | FKWSHDGKFFARMTL |
| 433 | LLDKKSLKISGIKDF |
| 491 | DCKLHWQKNGDYLCV |
| 499 | NGDYLCVKVDRTPKG |
| 663 | FQGRLLQKNSKDRFC |
| 688 | LLSQDQIKQIKKDLK |
| 704 | YSKIFEQKDRLSQSK |
| 711 | KDRLSQSKASKELVE |
| 714 | LSQSKASKELVERRR |
Function
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome
Protein Sequence
10
MQDAENVAAP
20
EASEQRAEPG
30
QQEPTAEAPP
40
REEPARPAAL
50
EGAGGEDPEA
60
GPGPDVPAEP
70
LADGEQKTDA
80
TPGASPPPSE
90
EPPTLAAGET
100
GQARDAAAEA
110
GSEGAGGEPG
120
GAAEDGGADE
130
PSFSDPEDFV
140
DDVSEEELLG
150
DVLKDRPQEA
160
DGIDSVIVVD
170
NVPQVGPDRL
180
EKLKNVIHKI
190
FSKFGKITND
200
FYPEEDGRTK
210
GYIFLEYAAP
220
AHALDAVKNA
230
DGYKLDKQHT
240
FRVNLFTDFD
250
KYMTISDEWD
260
IPEKQPFKDL
270
GNLRYWLEEA
280
ECRDQYSVIF
290
ESGDRTSIFW
300
NDVKDPVSIE
310
ERARWTETYV
320
RWSPKGTYLA
330
TFHQRGIALW
340
GGEKFKQIQR
350
FSHQGVQLID
360
FSPCERYLVT
370
FSPLMDTQDD
380
PQAIIIWDIL
390
TGQKKRGFHC
400
ESSAHWPIFK
410
WSHDGKFFAR
420
MTLDTLSIYE
430
TPSMGLLDKK
440
SLKISGIKDF
450
SWSPGGNIIA
460
FWVPEDKDIP
470
ARVTLMQLPS
480
RQEIRVRNLF
490
NVVDCKLHWQ
500
KNGDYLCVKV
510
DRTPKGTQGV
520
VTNFEIFRMR
530
EKQVPVDVVE
540
MKETIIAFAW
550
EPNGSKFAVL
560
HGEAPRISVS
570
FYHVKNNGKI
580
ELIKMFDKQQ
590
ANTIFWSPQG
600
QFVVLAGLRS
610
MNGALAFVDT
620
SDCTVMNIAE
630
HYMASDVEWD
640
PTGRYVVTSV
650
SWWSHKVDNA
660
YWLWTFQGRL
670
LQKNSKDRFC
680
QLLWRPRPPT
690
LLSQDQIKQI
700
KKDLKKYSKI
710
FEQKDRLSQS
720
KASKELVERR
730
RTMMEDFRKY
740
RKKAQELYME
750
QKNERLELRG
760
GVDTDELDSN
770
VDDWEEETIE
780
FFVTEEIIPL
GNQE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0010494 | cytoplasmic stress granule |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016282 | eukaryotic 43S preinitiation complex |
| Cellular Component | GO:0033290 | eukaryotic 48S preinitiation complex |
| Cellular Component | GO:0005852 | eukaryotic translation initiation factor 3 complex |
| Cellular Component | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0003743 | translation initiation factor activity |
| Molecular Function | GO:0031369 | translation initiation factor binding |
| Biological Process | GO:0001732 | formation of cytoplasmic translation initiation complex |
| Biological Process | GO:0075522 | IRES-dependent viral translational initiation |
| Biological Process | GO:0006446 | regulation of translational initiation |
| Biological Process | GO:0006413 | translational initiation |
| Biological Process | GO:0075525 | viral translational termination-reinitiation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.