Search Results

Overview

Uniprot IDM3TYW5
Protein NameGlutamine--tRNA ligase
Gene NameQARS
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
136 AINHHRSKLLVERYH
158 GEARAALKWADGKMI
25 HKARETLKNTALSAQ
309 FDDTNPEKEEAKFFT
394 FEAMRKGKFAEGEAT
496 LHYAVVSKRKILQLV
498 YAVVSKRKILQLVAA
620 FIERTDFKEEPEPGY
740 ALAKPFDKFQFERLG

Function

Glutamine--tRNA ligase. Plays a critical role in brain development

Protein Sequence

10 MAALDSLSLF 20 TGLGLSEHKA 30 RETLKNTALS 40 AQLREAATQA 50 QQTLGSTIDK 60 ATGTLLYGLA 70 SRLRDPRRLS 80 FLVSYIASRK 90 IHTETQLSAA 100 LEYVRSHPLD 110 PINTMDFEQE 120 CGVGVIVTPE 130 QIEEAVEAAI 140 NHHRSKLLVE 150 RYHFNMGLLM 160 GEARAALKWA 170 DGKMIKHEVD 180 MQVLHLLGPK 190 TESDLEKKPK 200 VAKARLEEKD 210 RVTAKDVVEN 220 GEAVVQTLSL 230 MEQLRGEALK 240 FHKPGENYKT 250 PGYVTTPHTM 260 DLLKQHLEIT 270 GGQIRTRFPP 280 EPNGILHIGH 290 AKAINFNFGY 300 AKANNGICFL 310 RFDDTNPEKE 320 EAKFFTAICD 330 MVAWLGYTPY 340 KVTYASDYFD 350 QLYAWAVELI 360 HRGLAYVCHQ 370 RGEELKGHNP 380 LPSPWRDRPI 390 EESLLLFEAM 400 RKGKFAEGEA 410 TLRMKLVMED 420 GKMDPVAYRV 430 KYTPHHRTGD 440 TWCIYPTYDY 450 THCLCDSIEH 460 ITHSLCTKEF 470 QARRSSYFWL 480 CNALDVYCPV 490 QWEYGRLNLH 500 YAVVSKRKIL 510 QLVAAGAVRD 520 WDDPRLFTLT 530 ALRRRGFPPE 540 AINNFCARVG 550 VTVAQTTMEP 560 HLLEACVRDV 570 LNDTAPRAMA 580 VLDSLQVVIT 590 NFPAAKLLDI 600 QVPNFPADET 610 KGFHQVPFGP 620 TVFIERTDFK 630 EEPEPGYKRL 640 AWGQPVGLRH 650 TGYVIELQHV 660 VKGPNGCVES 670 LEVTCRRADV 680 GEKPKAFIHW 690 VSQPLTCEIR 700 LYDRLFQHKN 710 PEDPAEVPGG 720 FLSDLNLASL 730 QVVEAALVDC 740 SVALAKPFDK 750 FQFERLGYFS 760 VDPDSRQGQL 770 VFNRTVTLKE DPGKV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0017101 aminoacyl-tRNA synthetase multienzyme complex
Cellular Component GO:0005829 cytosol
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0004819 glutamine-tRNA ligase activity
Molecular Function GO:0019901 protein kinase binding
Molecular Function GO:0004860 protein kinase inhibitor activity
Biological Process GO:0007420 brain development
Biological Process GO:0006425 glutaminyl-tRNA aminoacylation
Biological Process GO:2001234 negative regulation of apoptotic signaling pathway
Biological Process GO:0045892 negative regulation of DNA-templated transcription
Biological Process GO:0032873 negative regulation of stress-activated MAPK cascade

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.