Search Results
Overview
| Uniprot ID | O00287 |
|---|---|
| Protein Name | Regulatory factor X-associated protein |
| Gene Name | RFXAP |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 155 | ETTSQVAKQRKPWMC |
Function
Part of the RFX complex that binds to the X-box of MHC II promoters
Protein Sequence
10
MEAQGVAEGA
20
GPGAASGVPH
30
PAALAPAAAP
40
TLAPASVAAA
50
ASQFTLLVMQ
60
PCAGQDEAAA
70
PGGSVGAGKP
80
VRYLCEGAGD
90
GEEEAGEDEA
100
DLLDTSDPPG
110
GGESAASLED
120
LEDEETHSGG
130
EGSSGGARRR
140
GSGGGSMSKT
150
CTYEGCSETT
160
SQVAKQRKPW
170
MCKKHRNKMY
180
KDKYKKKKSD
190
QALNCGGTAS
200
TGSAGNVKLE
210
ESADNILSIV
220
KQRTGSFGDR
230
PARPTLLEQV
240
LNQKRLSLLR
250
SPEVVQFLQK
260
QQQLLNQQVL
270
EQRQQQFPGT
SM
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0090575 | RNA polymerase II transcription regulator complex |
| Molecular Function | GO:0003677 | DNA binding |
| Biological Process | GO:0045348 | positive regulation of MHC class II biosynthetic process |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
Reference
PMID: N/A