Search Results
Overview
| Uniprot ID | O00409 |
|---|---|
| Protein Name | Forkhead box protein N3 |
| Gene Name | FOXN3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 419 | SGYASQHKKRQHFAK |
| 420 | GYASQHKKRQHFAKA |
Function
Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints)
Protein Sequence
10
MGPVMPPSKK
20
PESSGISVSS
30
GLSQCYGGSG
40
FSKALQEDDD
50
LDFSLPDIRL
60
EEGAMEDEEL
70
TNLNWLHESK
80
NLLKSFGESV
90
LRSVSPVQDL
100
DDDTPPSPAH
110
SDMPYDARQN
120
PNCKPPYSFS
130
CLIFMAIEDS
140
PTKRLPVKDI
150
YNWILEHFPY
160
FANAPTGWKN
170
SVRHNLSLNK
180
CFKKVDKERS
190
QSIGKGSLWC
200
IDPEYRQNLI
210
QALKKTPYHP
220
HPHVFNTPPT
230
CPQAYQSTSG
240
PPIWPGSTFF
250
KRNGALLQDP
260
DIDAASAMML
270
LNTPPEIQAG
280
FPPGVIQNGA
290
RVLSRGLFPG
300
VRPLPITPIG
310
VTAAMRNGIT
320
SCRMRTESEP
330
SCGSPVVSGD
340
PKEDHNYSSA
350
KSSNARSTSP
360
TSDSISSSSS
370
SADDHYEFAT
380
KGSQEGSEGS
390
EGSFRSHESP
400
SDTEEDDRKH
410
SQKEPKDSLG
420
DSGYASQHKK
430
RQHFAKARKV
440
PSDTLPLKKR
450
RTEKPPESDD
460
EEMKEAAGSL
470
LHLAGIRSCL
480
NNITNRTAKG
490
QKEQKETTKN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0000987 | cis-regulatory region sequence-specific DNA binding |
| Molecular Function | GO:0003700 | DNA-binding transcription factor activity |
| Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0007095 | mitotic G2 DNA damage checkpoint signaling |
| Biological Process | GO:0045892 | negative regulation of DNA-templated transcription |
| Biological Process | GO:0006355 | regulation of DNA-templated transcription |
Reference
PMID: N/A