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Overview

Uniprot IDO00559
Protein NameReceptor-binding cancer antigen expressed on SiSo cells
Gene NameEBAG9
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
112 TQKIVIKKREPLNFG

Function

May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases

Protein Sequence

10 MAITQFRLFK 20 FCTCLATVFS 30 FLKRLICRSG 40 RGRKLSGDQI 50 TLPTTVDYSS 60 VPKQTDVEEW 70 TSWDEDAPTS 80 VKIEGGNGNV 90 ATQQNSLEQL 100 EPDYFKDMTP 110 TIRKTQKIVI 120 KKREPLNFGI 130 PDGSTGFSSR 140 LAATQDLPFI 150 HQSSELGDLD 160 TWQENTNAWE 170 EEEDAAWQAE 180 EVLRQQKLAD 190 REKRAAEQQR 200 KKMEKEAQRL 210 MKKEQNKIGV KLS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005794 Golgi apparatus
Cellular Component GO:0000139 Golgi membrane
Cellular Component GO:0030141 secretory granule
Molecular Function GO:0016505 peptidase activator activity involved in apoptotic process
Biological Process GO:0001558 regulation of cell growth

Reference

[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.