Search Results
Overview
| Uniprot ID | O08997 |
|---|---|
| Protein Name | Copper transport protein ATOX1 |
| Gene Name | Atox1 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 60 | ATLNKTGKAVSYLGP |
Function
Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity)
Protein Sequence
10
MPKHEFSVDM
20
TCEGCAEAVS
30
RVLNKLGGVE
40
FNIDLPNKKV
50
CIDSEHSSDT
60
LLATLNKTGK
AVSYLGPK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0051117 | ATPase binding |
| Molecular Function | GO:0016531 | copper chaperone activity |
| Molecular Function | GO:0005507 | copper ion binding |
| Molecular Function | GO:0032767 | copper-dependent protein binding |
| Molecular Function | GO:1903136 | cuprous ion binding |
| Biological Process | GO:0060003 | copper ion export |
| Biological Process | GO:0006825 | copper ion transport |
| Biological Process | GO:0006878 | intracellular copper ion homeostasis |
| Biological Process | GO:0043066 | negative regulation of apoptotic process |
| Biological Process | GO:0006979 | response to oxidative stress |
Reference
[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.
[2] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.
[3] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.