Search Results
Overview
| Uniprot ID | O09131 |
|---|---|
| Protein Name | Glutathione S-transferase omega-1 |
| Gene Name | Gsto1 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 136 | SFVRSKRKEDSPNLR |
Function
Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Also has glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid
Protein Sequence
10
MSGESSRSLG
20
KGSAPPGPVP
30
EGQIRVYSMR
40
FCPFAQRTLM
50
VLKAKGIRHE
60
VININLKNKP
70
EWFFEKNPLG
80
LVPVLENSQG
90
HLVTESVITC
100
EYLDEAYPEK
110
KLFPDDPYKK
120
ARQKMTLESF
130
SKVPPLIASF
140
VRSKRKEDSP
150
NLREALENEF
160
KKLEEGMDNY
170
KSFLGGDSPS
180
MVDYLTWPWF
190
QRLEALELKE
200
CLAHTPKLKL
210
WMAAMQQDPV
220
ASSHKIDAKT
230
YREYLNLYLQ
240
DSPEACDYGL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0005604 | basement membrane |
| Cellular Component | GO:0044297 | cell body |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0031965 | nuclear membrane |
| Molecular Function | GO:0045174 | glutathione dehydrogenase (ascorbate) activity |
| Molecular Function | GO:0004364 | glutathione transferase activity |
| Molecular Function | GO:0050610 | methylarsonate reductase activity |
| Molecular Function | GO:0016491 | oxidoreductase activity |
| Biological Process | GO:0071243 | cellular response to arsenic-containing substance |
| Biological Process | GO:0006749 | glutathione metabolic process |
| Biological Process | GO:0019853 | L-ascorbic acid biosynthetic process |
| Biological Process | GO:0019852 | L-ascorbic acid metabolic process |
| Biological Process | GO:0051280 | negative regulation of release of sequestered calcium ion into cytosol |
| Biological Process | GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol |
| Biological Process | GO:0014810 | positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion |
| Biological Process | GO:0010881 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion |
| Biological Process | GO:0010880 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum |
| Biological Process | GO:0042178 | xenobiotic catabolic process |
Reference
[1] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.