Search Results
Overview
| Uniprot ID | O14828 |
|---|---|
| Protein Name | Secretory carrier-associated membrane protein 3 |
| Gene Name | SCAMP3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 74 | PSLQPSRKLSPTEPK |
Function
Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface
Protein Sequence
10
MAQSRDGGNP
20
FAEPSELDNP
30
FQDPAVIQHR
40
PSRQYATLDV
50
YNPFETREPP
60
PAYEPPAPAP
70
LPPPSAPSLQ
80
PSRKLSPTEP
90
KNYGSYSTQA
100
SAAAATAELL
110
KKQEELNRKA
120
EELDRREREL
130
QHAALGGTAT
140
RQNNWPPLPS
150
FCPVQPCFFQ
160
DISMEIPQEF
170
QKTVSTMYYL
180
WMCSTLALLL
190
NFLACLASFC
200
VETNNGAGFG
210
LSILWVLLFT
220
PCSFVCWYRP
230
MYKAFRSDSS
240
FNFFVFFFIF
250
FVQDVLFVLQ
260
AIGIPGWGFS
270
GWISALVVPK
280
GNTAVSVLML
290
LVALLFTGIA
300
VLGIVMLKRI
310
HSLYRRTGAS
320
FQKAQQEFAA
330
GVFSNPAVRT
340
AAANAAAGAA
ENAFRAP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0055038 | recycling endosome membrane |
| Cellular Component | GO:0032588 | trans-Golgi network membrane |
| Molecular Function | GO:0031625 | ubiquitin protein ligase binding |
| Biological Process | GO:0006887 | exocytosis |
| Biological Process | GO:0006892 | post-Golgi vesicle-mediated transport |
| Biological Process | GO:0015031 | protein transport |
Reference
[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.
[2] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[3] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.