Search Results
Overview
| Uniprot ID | O35824 |
|---|---|
| Protein Name | DnaJ homolog subfamily A member 2 |
| Gene Name | Dnaja2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 152 | ACSGQGGKSGAVQKC |
| 39 | AKEYHPDKNPNAGDK |
Function
Co-chaperone of Hsc70. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro)
Protein Sequence
10
MANVADTKLY
20
DILGVPPGAS
30
ENELKKAYRK
40
LAKEYHPDKN
50
PNAGDKFKEI
60
SFAYEVLSNP
70
EKRELYDRYG
80
EQGLREGSGG
90
GGGMDDIFSH
100
IFGGGLFGFM
110
GNQSRSRNGR
120
RRGEDMMHPL
130
KVSLEDLYNG
140
KTTKLQLSKN
150
VLCSACSGQG
160
GKSGAVQKCS
170
ACRGRGVRIM
180
IRQLAPGMVQ
190
QMQSVCSDCN
200
GEGEVINEKD
210
RCKKCEGKKV
220
IKEVKILEVH
230
VDKGMKHGQR
240
ITFTGEADQA
250
PGVEPGDIVL
260
FVQEKEHEVF
270
QRDGNDLHMT
280
YKIGLVEALC
290
GFQFTFKHLD
300
ARQIVVKYPP
310
GKVIEPGCVR
320
VVRGEGMPQY
330
RNPFEKGDLY
340
IKFDVQFPEN
350
NWINPDKLSE
360
LEDLLPSRPE
370
VPNVIGETEE
380
VELQEFDSTR
390
GSGGGQRREA
400
YNDSSDEESS
410
SHHGPGVQCA
HQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016020 | membrane |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0001671 | ATPase activator activity |
| Molecular Function | GO:0030544 | Hsp70 protein binding |
| Molecular Function | GO:0051087 | protein-folding chaperone binding |
| Molecular Function | GO:0051082 | unfolded protein binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0018885 | carbon tetrachloride metabolic process |
| Biological Process | GO:0034605 | cellular response to heat |
| Biological Process | GO:0042026 | protein refolding |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.