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Overview

Uniprot IDO43169
Protein NameCytochrome b5 type B
Gene NameCYB5B
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
34 YRLEEVAKRNSLKEL

Function

Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases

Protein Sequence

10 MSGSMATAEA 20 SGSDGKGQEV 30 ETSVTYYRLE 40 EVAKRNSLKE 50 LWLVIHGRVY 60 DVTRFLNEHP 70 GGEEVLLEQA 80 GVDASESFED 90 VGHSSDAREM 100 LKQYYIGDIH 110 PSDLKPESGS 120 KDPSKNDTCK 130 SCWAYWILPI 140 IGAVLLGFLY 150 RYYTSESKSS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005789 endoplasmic reticulum membrane
Cellular Component GO:0016020 membrane
Cellular Component GO:0005741 mitochondrial outer membrane
Cellular Component GO:1903958 nitric-oxide synthase complex
Molecular Function GO:0020037 heme binding
Molecular Function GO:0046872 metal ion binding
Biological Process GO:0006809 nitric oxide biosynthetic process
Biological Process GO:0006979 response to oxidative stress
Biological Process GO:0006805 xenobiotic metabolic process

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.