Search Results
Overview
| Uniprot ID | O43570 |
|---|---|
| Protein Name | Carbonic anhydrase 12 |
| Gene Name | CA12 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 343 | DNKGVIYKPATKMET |
| 347 | VIYKPATKMETEAHA |
Function
Reversible hydration of carbon dioxide
Protein Sequence
10
MPRRSLHAAA
20
VLLLVILKEQ
30
PSSPAPVNGS
40
KWTYFGPDGE
50
NSWSKKYPSC
60
GGLLQSPIDL
70
HSDILQYDAS
80
LTPLEFQGYN
90
LSANKQFLLT
100
NNGHSVKLNL
110
PSDMHIQGLQ
120
SRYSATQLHL
130
HWGNPNDPHG
140
SEHTVSGQHF
150
AAELHIVHYN
160
SDLYPDASTA
170
SNKSEGLAVL
180
AVLIEMGSFN
190
PSYDKIFSHL
200
QHVKYKGQEA
210
FVPGFNIEEL
220
LPERTAEYYR
230
YRGSLTTPPC
240
NPTVLWTVFR
250
NPVQISQEQL
260
LALETALYCT
270
HMDDPSPREM
280
INNFRQVQKF
290
DERLVYTSFS
300
QVQVCTAAGL
310
SLGIILSLAL
320
AGILGICIVV
330
VVSIWLFRRK
340
SIKKGDNKGV
350
IYKPATKMET
EAHA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016324 | apical plasma membrane |
| Cellular Component | GO:0016323 | basolateral plasma membrane |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0004089 | carbonate dehydratase activity |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0055064 | chloride ion homeostasis |
| Biological Process | GO:0044849 | estrous cycle |
Reference
[1] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.