Search Results
Overview
| Uniprot ID | O43795 |
|---|---|
| Protein Name | Unconventional myosin-Ib |
| Gene Name | MYO1B |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 1124 | NGSVPTCKRKNNRLL |
Function
Motor protein that may participate in process critical to neuronal development and function such as cell migration, neurite outgrowth and vesicular transport
Protein Sequence
10
MAKMEVKTSL
20
LDNMIGVGDM
30
VLLEPLNEET
40
FINNLKKRFD
50
HSEIYTYIGS
60
VVISVNPYRS
70
LPIYSPEKVE
80
EYRNRNFYEL
90
SPHIFALSDE
100
AYRSLRDQDK
110
DQCILITGES
120
GAGKTEASKL
130
VMSYVAAVCG
140
KGAEVNQVKE
150
QLLQSNPVLE
160
AFGNAKTVRN
170
DNSSRFGKYM
180
DIEFDFKGDP
190
LGGVISNYLL
200
EKSRVVKQPR
210
GERNFHVFYQ
220
LLSGASEELL
230
NKLKLERDFS
240
RYNYLSLDSA
250
KVNGVDDAAN
260
FRTVRNAMQI
270
VGFMDHEAES
280
VLAVVAAVLK
290
LGNIEFKPES
300
RVNGLDESKI
310
KDKNELKEIC
320
ELTGIDQSVL
330
ERAFSFRTVE
340
AKQEKVSTTL
350
NVAQAYYARD
360
ALAKNLYSRL
370
FSWLVNRINE
380
SIKAQTKVRK
390
KVMGVLDIYG
400
FEIFEDNSFE
410
QFIINYCNEK
420
LQQIFIELTL
430
KEEQEEYIRE
440
DIEWTHIDYF
450
NNAIICDLIE
460
NNTNGILAML
470
DEECLRPGTV
480
TDETFLEKLN
490
QVCATHQHFE
500
SRMSKCSRFL
510
NDTSLPHSCF
520
RIQHYAGKVL
530
YQVEGFVDKN
540
NDLLYRDLSQ
550
AMWKASHALI
560
KSLFPEGNPA
570
KINLKRPPTA
580
GSQFKASVAT
590
LMKNLQTKNP
600
NYIRCIKPND
610
KKAAHIFNEA
620
LVCHQIRYLG
630
LLENVRVRRA
640
GYAFRQAYEP
650
CLERYKMLCK
660
QTWPHWKGPA
670
RSGVEVLFNE
680
LEIPVEEYSF
690
GRSKIFIRNP
700
RTLFKLEDLR
710
KQRLEDLATL
720
IQKIYRGWKC
730
RTHFLLMKKS
740
QIVIAAWYRR
750
YAQQKRYQQT
760
KSSALVIQSY
770
IRGWKARKIL
780
RELKHQKRCK
790
EAVTTIAAYW
800
HGTQARRELR
810
RLKEEARNKH
820
AIAVIWAYWL
830
GSKARRELKR
840
LKEEARRKHA
850
VAVIWAYWLG
860
LKVRREYRKF
870
FRANAGKKIY
880
EFTLQRIVQK
890
YFLEMKNKMP
900
SLSPIDKNWP
910
SRPYLFLDST
920
HKELKRIFHL
930
WRCKKYRDQF
940
TDQQKLIYEE
950
KLEASELFKD
960
KKALYPSSVG
970
QPFQGAYLEI
980
NKNPKYKKLK
990
DAIEEKIIIA
1000
EVVNKINRAN
1010
GKSTSRIFLL
1020
TNNNLLLADQ
1030
KSGQIKSEVP
1040
LVDVTKVSMS
1050
SQNDGFFAVH
1060
LKEGSEAASK
1070
GDFLFSSDHL
1080
IEMATKLYRT
1090
TLSQTKQKLN
1100
IEISDEFLVQ
1110
FRQDKVCVKF
1120
IQGNQKNGSV
1130
PTCKRKNNRL
LEVAVP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015629 | actin cytoskeleton |
| Biological Process | GO:0030048 | actin filament-based movement |
| Biological Process | GO:0006897 | endocytosis |
| Biological Process | GO:0006892 | post-Golgi vesicle-mediated transport |
| Cellular Component | GO:0005884 | actin filament |
| Cellular Component | GO:0005903 | brush border |
| Cellular Component | GO:0071944 | cell periphery |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005769 | early endosome |
| Cellular Component | GO:0010008 | endosome membrane |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0030175 | filopodium |
| Cellular Component | GO:0005902 | microvillus |
| Cellular Component | GO:0016459 | myosin complex |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0051015 | actin filament binding |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0045296 | cadherin binding |
| Molecular Function | GO:0005516 | calmodulin binding |
| Molecular Function | GO:0000146 | microfilament motor activity |
| Molecular Function | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding |
| Molecular Function | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding |
| Biological Process | GO:0051017 | actin filament bundle assembly |
| Biological Process | GO:0007015 | actin filament organization |
Reference
[1] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.