Search Results
Overview
| Uniprot ID | O43822 |
|---|---|
| Protein Name | Cilia- and flagella-associated protein 410 |
| Gene Name | CFAP410 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 22 | SELHSVRKLNCWGSR |
Function
Plays a role in cilia formation and/or maintenance (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987). Involved in DNA damage repair (PubMed:26290490)
Protein Sequence
10
MKLTRKMVLT
20
RAKASELHSV
30
RKLNCWGSRL
40
TDISICQEMP
50
SLEVITLSVN
60
SISTLEPVSR
70
CQRLSELYLR
80
RNRIPSLAEL
90
FYLKGLPRLR
100
VLWLAENPCC
110
GTSPHRYRMT
120
VLRTLPRLQK
130
LDNQAVTEEE
140
LSRALSEGEE
150
ITAAPEREGT
160
GHGGPKLCCT
170
LSSLSSAAET
180
GRDPLDSEEE
190
ATSGAQDERG
200
LKPPSRGQFP
210
SLSARDASSS
220
HRGRNVLTAI
230
LLLLRELDAE
240
GLEAVQQTVG
250
SRLQALRGEE
VQEHAE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0036064 | ciliary basal body |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0032391 | photoreceptor connecting cilium |
| Cellular Component | GO:0001750 | photoreceptor outer segment |
| Cellular Component | GO:0005886 | plasma membrane |
| Biological Process | GO:0030030 | cell projection organization |
| Biological Process | GO:0007010 | cytoskeleton organization |
| Biological Process | GO:0006974 | DNA damage response |
Reference
[1] Yan M, Tu H, Tang S, Gai Z, Shi Q et al.. Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.. Mol Cell Proteomics 24(12):101439. 2025 Dec. PMID: 41192556.