Search Results
Overview
| Uniprot ID | O43896 |
|---|---|
| Protein Name | Kinesin-like protein KIF1C |
| Gene Name | KIF1C |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 294 | DMQSKKRKSDFIPYR |
| 496 | TVGVFSPKKTPHLVN |
| 497 | VGVFSPKKTPHLVNL |
Function
Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility
Protein Sequence
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0008574 | plus-end-directed microtubule motor activity |
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:1904115 | axon cytoplasm |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0005871 | kinesin complex |
| Cellular Component | GO:0005874 | microtubule |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0003774 | cytoskeletal motor activity |
| Molecular Function | GO:0008017 | microtubule binding |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:1990048 | anterograde neuronal dense core vesicle transport |
| Biological Process | GO:1990049 | retrograde neuronal dense core vesicle transport |
| Biological Process | GO:0006890 | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| Biological Process | GO:0016192 | vesicle-mediated transport |
Reference
[1] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.
[2] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.
[3] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.