Search Results
Overview
| Uniprot ID | O43913 |
|---|---|
| Protein Name | Origin recognition complex subunit 5 |
| Gene Name | ORC5 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 330 | TDKRFFLKHHGKIKK |
Function
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication
Protein Sequence
10
MPHLENVVLC
20
RESQVSILQS
30
LFGERHHFSF
40
PSIFIYGHTA
50
SGKTYVTQTL
60
LKTLELPHVF
70
VNCVECFTLR
80
LLLEQILNKL
90
NHLSSSEDGC
100
STEITCETFN
110
DFVRLFKQVT
120
TAENLKDQTV
130
YIVLDKAEYL
140
RDMEANLLPG
150
FLRLQELADR
160
NVTVLFLSEI
170
VWEKFRPNTG
180
CFEPFVLYFP
190
DYSIGNLQKI
200
LSHDHPPEYS
210
ADFYAAYINI
220
LLGVFYTVCR
230
DLKELRHLAV
240
LNFPKYCEPV
250
VKGEASERDT
260
RKLWRNIEPH
270
LKKAMQTVYL
280
REISSSQWEK
290
LQKDDTDPGQ
300
LKGLSAHTHV
310
ELPYYSKFIL
320
IAAYLASYNP
330
ARTDKRFFLK
340
HHGKIKKTNF
350
LKKHEKTSNH
360
LLGPKPFPLD
370
RLLAILYSIV
380
DSRVAPTANI
390
FSQITSLVTL
400
QLLTLVGHDD
410
QLDGPKYKCT
420
VSLDFIRAIA
430
RTVNFDIIKY
LYDFL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0000781 | chromosome, telomeric region |
| Cellular Component | GO:0005664 | nuclear origin of replication recognition complex |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0000808 | origin recognition complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0003688 | DNA replication origin binding |
| Molecular Function | GO:0000166 | nucleotide binding |
| Biological Process | GO:0006260 | DNA replication |
| Biological Process | GO:0006270 | DNA replication initiation |
| Biological Process | GO:0006275 | regulation of DNA replication |
Reference
PMID: N/A