Search Results
Overview
| Uniprot ID | O43920 |
|---|---|
| Protein Name | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 |
| Gene Name | NDUFS5 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 8 | MPFLDIQKRFGLNID |
Function
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Protein Sequence
10
MPFLDIQKRF
20
GLNIDRWLTI
30
QSGEQPYKMA
40
GRCHAFEKEW
50
IECAHGIGYT
60
RAEKECKIEY
70
DDFVECLLRQ
80
KTMRRAGTIR
90
KQRDKLIKEG
100
KYTPPPHHIG
KGEPRP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Molecular Function | GO:0008137 | NADH dehydrogenase (ubiquinone) activity |
| Biological Process | GO:0009060 | aerobic respiration |
| Biological Process | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone |
| Biological Process | GO:0032981 | mitochondrial respiratory chain complex I assembly |
| Biological Process | GO:0042776 | proton motive force-driven mitochondrial ATP synthesis |
| Cellular Component | GO:0005758 | mitochondrial intermembrane space |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0045271 | respiratory chain complex I |
Reference
[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.