Search Results
Overview
| Uniprot ID | O60234 |
|---|---|
| Protein Name | Glia maturation factor gamma |
| Gene Name | GMFG |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 25 | LRKFRFRKETDNAAI |
Function
No function data available.
Protein Sequence
10
MSDSLVVCEV
20
DPELTEKLRK
30
FRFRKETDNA
40
AIIMKVDKDR
50
QMVVLEEEFQ
60
NISPEELKME
70
LPERQPRFVV
80
YSYKYVHDDG
90
RVSYPLCFIF
100
SSPVGCKPEQ
110
QMMYAGSKNR
120
LVQTAELTKV
130
FEIRTTDDLT
140
EAWLQEKLSF
FR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030864 | cortical actin cytoskeleton |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:1904813 | ficolin-1-rich granule lumen |
| Cellular Component | GO:0034774 | secretory granule lumen |
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0071933 | Arp2/3 complex binding |
| Molecular Function | GO:0008047 | enzyme activator activity |
| Molecular Function | GO:0008083 | growth factor activity |
| Molecular Function | GO:0004860 | protein kinase inhibitor activity |
| Biological Process | GO:0071846 | actin filament debranching |
| Biological Process | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation |
| Biological Process | GO:0006468 | protein phosphorylation |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Yang YH, Wang QC, Kong J, Yang JT, Liu JF. Global profiling of lysine lactylation in human lungs.. Proteomics 23(15):e2200437. 2023 Aug. PMID: 37170646.
[3] Guo X, Ren X, Yan C, Huang H. Quantitative Proteomics Reveals the Role of Lysine Lactylation in Lenalidomide-Resistance in Multiple Myeloma Cells.. ACS Chem Biol 20(7):1728-1738. 2025 Jul 18. PMID: 40590393.