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Overview

Uniprot ID	O60447
Protein Name	Ecotropic viral integration site 5 protein homolog
Gene Name	EVI5
Organism	Homo sapiens

Kla Sites from experimental identification

Position	Flanking peptide
679	EIQKEEGKLQGQLNK

Function

Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase. May play a role in cytokinesis

Protein Sequence

10 MVTNKMTAAF 20 RNPSGKQVAT 30 DKVAEKLSST 40 LSWVKNTVSH 50 TVSQMASQVA 60 SPSTSLHTTS 70 SSTTLSTPAL 80 SPSSPSQLSP 90 DDLELLAKLE 100 EQNRLLETDS 110 KSLRSVNGSR 120 RNSGSSLVSS 130 SSASSNLSHL 140 EEDSWILWGR 150 IVNEWEDVRK 160 KKEKQVKELV 170 HKGIPHHFRA 180 IVWQLLCSAQ 190 SMPIKDQYSE 200 LLKMTSPCEK 210 LIRRDIARTY 220 PEHNFFKEKD 230 SLGQEVLFNV 240 MKAYSLVDRE 250 VGYCQGSAFI 260 VGLLLMQMPE 270 EEAFCVFVKL 280 MQDYRLRELF 290 KPSMAELGLC 300 MYQFECMIQE 310 HLPELFVHFQ 320 SQSFHTSMYA 330 SSWFLTIFLT 340 TFPLPIATRI 350 FDIFMSEGLE 360 IVFRVGLALL 370 QMNQAELMQL 380 DMEGMLQHFQ 390 KVIPHQFDGV 400 PDKLIQAAYQ 410 VKYNSKKMKK 420 LEKEYTTIKT 430 KEMEEQVEIK 440 RLRTENRLLK 450 QRIETLEKHK 460 CSSNYNEDFV 470 LQLEKELVQA 480 RLSEAESQCA 490 LKEMQDKVLD 500 IEKRNNSLPD 510 ENNIARLQEE 520 LIAVKLREAE 530 AIMGLKELRQ 540 QVKDLEEHWQ 550 RHLARTTGRW 560 KDPPKKNAMN 570 ELQDELMTIR 580 LREAETQAEI 590 REIKQRMMEM 600 ETQNQINSNH 610 LRRAEQEVIS 620 LQEKVQYLSA 630 QNKGLLTQLS 640 EAKRKQAEIE 650 CKNKEEVMAV 660 RLREADSIAA 670 VAELRQHIAE 680 LEIQKEEGKL 690 QGQLNKSDSN 700 QYIGELKDQI 710 AELNHELRCL 720 KGQRGFSGQP 730 PFDGIHIVNH 740 LIGDDESFHS 750 SDEDFIDNSL 760 QETGVGFPLH 770 GKSGSMSLDP 780 AVADGSESET 790 EDSVLETRES 800 NQVVQKERPP 810 RRRESYSTTV

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005813	centrosome
Cellular Component	GO:0005829	cytosol
Cellular Component	GO:0005634	nucleus
Cellular Component	GO:0005819	spindle
Molecular Function	GO:0005096	GTPase activator activity
Molecular Function	GO:0031267	small GTPase binding
Biological Process	GO:0051301	cell division
Biological Process	GO:0043547	positive regulation of GTPase activity
Biological Process	GO:0042147	retrograde transport, endosome to Golgi

Reference

PMID: N/A