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Overview

Uniprot IDO60831
Protein NamePRA1 family protein 2
Gene NamePRAF2
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
152 LKNKIENKIESIGLK

Function

May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptotic role in cerulenin-induced neuroblastoma apoptosis

Protein Sequence

10 MSEVRLPPLR 20 ALDDFVLGSA 30 RLAAPDPCDP 40 QRWCHRVINN 50 LLYYQTNYLL 60 CFGIGLALAG 70 YVRPLHTLLS 80 ALVVAVALGV 90 LVWAAETRAA 100 VRRCRRSHPA 110 ACLAAVLAVG 120 LLVLWVAGGA 130 CTFLFSIAGP 140 VLLILVHASL 150 RLRNLKNKIE 160 NKIESIGLKR 170 TPMGLLLEAL GQEQEAGS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0010008 endosome membrane
Cellular Component GO:0098982 GABA-ergic synapse
Cellular Component GO:0098978 glutamatergic synapse
Cellular Component GO:0016020 membrane
Cellular Component GO:0098794 postsynapse
Cellular Component GO:0098793 presynapse
Biological Process GO:0015813 L-glutamate transmembrane transport
Biological Process GO:0015031 protein transport

Reference

[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.