Search Results
Overview
| Uniprot ID | O62839 |
|---|---|
| Protein Name | Catalase |
| Gene Name | CAT |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 237 | VYCKFHYKTDQGIKN |
| 243 | YKTDQGIKNLSVEDA |
| 476 | DAQLFIQKKAVKNFS |
Function
Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells
Protein Sequence
10
MADNRDPASD
20
QMKHWKEQRA
30
AQKPDILTTG
40
SGNPIGDKLN
50
ILTAGPRGPL
60
LVQDVVFTDE
70
MAHFDRERIP
80
ERVVHAKGAG
90
AFGYFEVTHD
100
ITRFSKAKVF
110
EHVGKRTPIA
120
VRFSTVAGES
130
GSADTVRDPR
140
GFAVKFYTED
150
GNWDLVGNNT
160
PIFFIRDAIL
170
FPSFIHSQKR
180
NPQTHLKDPD
190
MVWDFWSLRP
200
ESLHQVSFLF
210
SDRGIPDGHR
220
HMNGYGSHTF
230
KLVNEKGEAV
240
YCKFHYKTDQ
250
GIKNLSVEDA
260
ARLPQEDPDY
270
GIRDLFNAIA
280
TGNYPSWTFY
290
IQVMTFQEAE
300
AFPFNPFDLT
310
KVWPHSEYPL
320
IPVGKLVLNR
330
NPVNYFAEVE
340
QMAFDPSNMP
350
PGIEPSPDKM
360
LQGRLFGYPD
370
THRHRLGANY
380
LQIPVNCPFR
390
ARVANYQRDG
400
PMCFQDNQGG
410
APNYYPNSFS
420
APEQTHSALE
430
HCTRYSGDVQ
440
RFNSANEDNV
450
TQVRTFYLNV
460
LNEEERKRLC
470
ENIAGHLKDA
480
QLFIQKKAVK
490
NFSDVHPDYG
500
ARIQALLDKY
510
NAEXPENAVH
520
TYVQAGSHLA
AREKANL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005782 | peroxisomal matrix |
| Cellular Component | GO:0005777 | peroxisome |
| Molecular Function | GO:0004096 | catalase activity |
| Molecular Function | GO:0020037 | heme binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:0042744 | hydrogen peroxide catabolic process |
| Biological Process | GO:0051781 | positive regulation of cell division |
| Biological Process | GO:0042542 | response to hydrogen peroxide |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.