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Overview

Uniprot IDO70209
Protein NamePDZ and LIM domain protein 3
Gene NamePdlim3
OrganismMus musculus

Kla Sites from experimental identification

Position Flanking peptide
97 PQVSEDGKAHPFKIN

Function

May play a role in the organization of actin filament arrays within muscle cells

Protein Sequence

10 MPQNVVLPGP 20 APWGFRLSGG 30 IDFNQPLVIT 40 RITPGSKAAA 50 ANLCPGDVIL 60 AIDGFGTESM 70 THADAQDRIK 80 AASYQLCLKI 90 DRAETRLWSP 100 QVSEDGKAHP 110 FKINLEAEPQ 120 EFKPIGTAHN 130 RRAQPFVAAA 140 NIDDKRQVVS 150 ASYNSPIGLY 160 STSNIQDALH 170 GQLRGLIPGS 180 LQNEPTASVP 190 PQSDVYRMLH 200 DNRDDPAAPR 210 QSGSFRVLQD 220 LVNDGPDDRP 230 AGTRSVRAPV 240 TKVHGGAGSA 250 QRMPLCDKCG 260 SGIVGAVVKA 270 RDKYRHPECF 280 VCADCNLNLK 290 QKGYFFVEGE 300 LYCETHARAR 310 TRPPEGYDTV TLYPKA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0015629 actin cytoskeleton
Cellular Component GO:0005912 adherens junction
Cellular Component GO:0005829 cytosol
Cellular Component GO:0031941 filamentous actin
Cellular Component GO:0001725 stress fiber
Cellular Component GO:0030018 Z disc
Molecular Function GO:0003779 actin binding
Molecular Function GO:0042805 actinin binding
Molecular Function GO:0008092 cytoskeletal protein binding
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0051371 muscle alpha-actinin binding
Molecular Function GO:0008307 structural constituent of muscle
Biological Process GO:0030036 actin cytoskeleton organization
Biological Process GO:0007015 actin filament organization
Biological Process GO:0007507 heart development
Biological Process GO:0061061 muscle structure development

Reference

[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.