Search Results

Overview

Uniprot ID	O75391
Protein Name	Sperm-associated antigen 7
Gene Name	SPAG7
Organism	Homo sapiens

Kla Sites from experimental identification

Position	Flanking peptide
166	PASDYKDKYSHLIGK
173	KYSHLIGKGAAKDAA
177	LIGKGAAKDAAHMLQ
197	GCVPVANKRDTRSIE
36	EQAARLKKLQEQEKQ

Function

No function data available.

Protein Sequence

10 MADLLGSILS 20 SMEKPPSLGD 30 QETRRKAREQ 40 AARLKKLQEQ 50 EKQQKVEFRK 60 RMEKEVSDFI 70 QDSGQIKKKF 80 QPMNKIERSI 90 LHDVVEVAGL 100 TSFSFGEDDD 110 CRYVMIFKKE 120 FAPSDEELDS 130 YRRGEEWDPQ 140 KAEEKRKLKE 150 LAQRQEEEAA 160 QQGPVVVSPA 170 SDYKDKYSHL 180 IGKGAAKDAA 190 HMLQANKTYG 200 CVPVANKRDT 210 RSIEEAMNEI 220 RAKKRLRQSG EELPPTS

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005654	nucleoplasm
Molecular Function	GO:0003676	nucleic acid binding

Reference

[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.

[2] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.

[3] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.

[4] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.

[5] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.