Search Results
Overview
| Uniprot ID | O75508 |
|---|---|
| Protein Name | Claudin-11 |
| Gene Name | CLDN11 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 116 | GQEPGVAKYRRAQLA |
| 203 | SSSPTHAKSAHV*** |
| 43 | YTIPTCRKLDELGSK |
Function
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity
Protein Sequence
10
MVATCLQVVG
20
FVTSFVGWIG
30
VIVTTSTNDW
40
VVTCGYTIPT
50
CRKLDELGSK
60
GLWADCVMAT
70
GLYHCKPLVD
80
ILILPGYVQA
90
CRALMIAASV
100
LGLPAILLLL
110
TVLPCIRMGQ
120
EPGVAKYRRA
130
QLAGVLLILL
140
ALCALVATIW
150
FPVCAHRETT
160
IVSFGYSLYA
170
GWIGAVLCLV
180
GGCVILCCAG
190
DAQAFGENRF
200
YYTAGSSSPT
HAKSAHV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0045178 | basal part of cell |
| Cellular Component | GO:0005923 | bicellular tight junction |
| Cellular Component | GO:0030054 | cell junction |
| Cellular Component | GO:0005883 | neurofilament |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0070160 | tight junction |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0005198 | structural molecule activity |
| Biological Process | GO:0016338 | calcium-independent cell-cell adhesion |
| Biological Process | GO:0007155 | cell adhesion |
| Biological Process | GO:0120192 | tight junction assembly |
Reference
[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.