Search Results
Overview
| Uniprot ID | O75683 |
|---|---|
| Protein Name | Surfeit locus protein 6 |
| Gene Name | SURF6 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 17 | YLQSLAKKICSHSAP |
| 34 | QARTRAGKTQGSETA |
Function
Binds to both DNA and RNA in vitro, with a stronger binding capacity for RNA. May represent a nucleolar constitutive protein involved in ribosomal biosynthesis or assembly (By similarity)
Protein Sequence
10
MASLLAKDAY
20
LQSLAKKICS
30
HSAPEQQART
40
RAGKTQGSET
50
AGPPKKKRKK
60
TQKKFRKREE
70
KAAEHKAKSL
80
GEKSPAASGA
90
RRPEAAKEEA
100
AWASSSAGNP
110
ADGLATEPES
120
VFALDVLRQR
130
LHEKIQEARG
140
QGSAKELSPA
150
ALEKRRRRKQ
160
ERDRKKRKRK
170
ELRAKEKARK
180
AEEATEAQEV
190
VEATPEGACT
200
EPREPPGLIF
210
NKVEVSEDEP
220
ASKAQRRKEK
230
RQRVKGNLTP
240
LTGRNYRQLL
250
ERLQARQSRL
260
DELRGQDEGK
270
AQELEAKMKW
280
TNLLYKAEGV
290
KIRDDERLLQ
300
EALKRKEKRR
310
AQRQRRWEKR
320
TAGVVEKMQQ
330
RQDRRRQNLR
340
RKKAARAERR
350
LLRARKKGRI
360
LPQDLERAGL
V
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005694 | chromosome |
| Cellular Component | GO:0001652 | granular component |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0140693 | molecular condensate scaffold activity |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0042273 | ribosomal large subunit biogenesis |
| Biological Process | GO:0042274 | ribosomal small subunit biogenesis |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.