Search Results
Overview
| Uniprot ID | O75940 |
|---|---|
| Protein Name | Survival of motor neuron-related-splicing factor 30 |
| Gene Name | SMNDC1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 142 | SGNKPMSKKEMIAQQ |
| 143 | GNKPMSKKEMIAQQR |
| 177 | EREDQKVKWQQFNNR |
| 229 | TQYQDTSKYNVRHLM |
Function
Involved in spliceosome assembly
Protein Sequence
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015030 | Cajal body |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0016604 | nuclear body |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0006915 | apoptotic process |
| Biological Process | GO:0006397 | mRNA processing |
| Biological Process | GO:0000375 | RNA splicing, via transesterification reactions |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.
[3] Chao L, Xu Y, Yang Y, Ao X, Liang J. Identification of lactylation-related biomarkers for diagnosis, prognosis, and treatment responsiveness in triple-negative breast cancer.. World J Surg Oncol 24(1):77. 2026 Jan 22. PMID: 41566505.
[4] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.