Search Results

Overview

Uniprot IDO88791
Protein Name-
Gene NameHmga2
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
34 RGRGRPRKQPQEPTC

Function

No function data available.

Protein Sequence

10 MSARGEGAGQ 20 PSTSAQGQPA 30 TPAPQKRGRG 40 RPRKQPQEPT 50 CEPSPKRPRG 60 RPKGSKNKSP 70 SKAAQKKAET 80 IGEKRPRGRP 90 RKWPQQIVQK 100 PAQETEETSS QESAEED

Gene Ontology

Classification GO ID Description
Molecular Function GO:0003712 transcription coregulator activity
Cellular Component GO:0000228 nuclear chromosome
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Cellular Component GO:0032993 protein-DNA complex
Cellular Component GO:0035985 senescence-associated heterochromatin focus
Cellular Component GO:0071141 SMAD protein complex
Molecular Function GO:0051575 5'-deoxyribose-5-phosphate lyase activity
Molecular Function GO:0070742 C2H2 zinc finger domain binding
Molecular Function GO:0035497 cAMP response element binding
Molecular Function GO:0008301 DNA binding, bending
Molecular Function GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
Molecular Function GO:0019899 enzyme binding
Molecular Function GO:0035501 MH1 domain binding
Molecular Function GO:0035500 MH2 domain binding
Molecular Function GO:0003680 minor groove of adenine-thymine-rich DNA binding
Molecular Function GO:0003676 nucleic acid binding
Molecular Function GO:0031492 nucleosomal DNA binding
Molecular Function GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding
Molecular Function GO:0046332 SMAD binding
Molecular Function GO:0000976 transcription cis-regulatory region binding
Molecular Function GO:0003714 transcription corepressor activity
Biological Process GO:0060612 adipose tissue development
Biological Process GO:0030325 adrenal gland development
Biological Process GO:0006284 base-excision repair
Biological Process GO:0021846 cell proliferation in forebrain
Biological Process GO:0002062 chondrocyte differentiation
Biological Process GO:0035988 chondrocyte proliferation
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0035987 endodermal cell differentiation
Biological Process GO:0001837 epithelial to mesenchymal transition
Biological Process GO:0060441 epithelial tube branching involved in lung morphogenesis
Biological Process GO:0045444 fat cell differentiation
Biological Process GO:0060613 fat pad development
Biological Process GO:0031507 heterochromatin formation
Biological Process GO:0043922 host-mediated suppression of viral transcription
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0060428 lung epithelium development
Biological Process GO:0008584 male gonad development
Biological Process GO:0048762 mesenchymal cell differentiation
Biological Process GO:0048333 mesodermal cell differentiation
Biological Process GO:0003131 mesodermal-endodermal cell signaling
Biological Process GO:0035264 multicellular organism growth
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0048712 negative regulation of astrocyte differentiation
Biological Process GO:2000773 negative regulation of cellular senescence
Biological Process GO:0043392 negative regulation of DNA binding
Biological Process GO:0045892 negative regulation of DNA-templated transcription
Biological Process GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining
Biological Process GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway
Biological Process GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT
Biological Process GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0030178 negative regulation of Wnt signaling pathway
Biological Process GO:0090402 oncogene-induced cell senescence
Biological Process GO:0021983 pituitary gland development
Biological Process GO:0045766 positive regulation of angiogenesis
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0071864 positive regulation of cell proliferation in bone marrow
Biological Process GO:0045893 positive regulation of DNA-templated transcription
Biological Process GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0040018 positive regulation of multicellular organism growth
Biological Process GO:0071902 positive regulation of protein serine/threonine kinase activity
Biological Process GO:2000648 positive regulation of stem cell proliferation
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0010564 regulation of cell cycle process
Biological Process GO:0006355 regulation of DNA-templated transcription
Biological Process GO:0060123 regulation of growth hormone secretion
Biological Process GO:0090276 regulation of peptide hormone secretion
Biological Process GO:2000036 regulation of stem cell population maintenance
Biological Process GO:0009615 response to virus
Biological Process GO:0035019 somatic stem cell population maintenance
Biological Process GO:0007283 spermatogenesis
Biological Process GO:0048863 stem cell differentiation

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.