Search Results

Overview

Uniprot IDO88954
Protein NameMAGUK p55 subfamily member 3
Gene NameMpp3
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
144 IVRLVKNKEPLGATI

Function

Participates in cell spreading through the phosphoinositide-3-kinase (PI3K) pathway by connecting CADM1 to DLG1 and the regulatory subunit of phosphoinositide-3-kinase (PI3K) (By similarity). Stabilizes HTR2C at the plasma membrane and prevents its desensitization. May participates in the maintenance of adherens junctions (By similarity)

Protein Sequence

10 MPVLSEDSGL 20 HETLALLTSQ 30 LRPDSNHREE 40 MGFLRDVFSE 50 KSLGYLMKIH 60 EKLRYYERQS 70 PTPVLHSAMA 80 LAEDVMEELQ 90 AASVHSDERE 100 LLQLLSTPHL 110 RAVLMVHDTV 120 AQKNFDPVLP 130 PLPDNIDEDF 140 EEESVKIVRL 150 VKNKEPLGAT 160 IRRDEHSGAV 170 VVARIMRGGA 180 ADRSGLVHVG 190 DELREVNGIT 200 VLHKRPDEIS 210 QILAQSQGSI 220 TLKIIPATQE 230 EDRFKESKVF 240 MRALFHYDPR 250 EDRAIPCQEA 260 GLPFQQRQVL 270 EVVSQDDPTW 280 WQAKRVGDTN 290 LRAGLIPSKQ 300 FQERRLSYRR 310 TTGTIPSPQN 320 LRKPLYDQPC 330 DKETCDCDGY 340 FKGHYVAGLR 350 RSFRLGCRER 360 LTGSQEVKVP 370 VGAESQVLLT 380 YEEVARYQHQ 390 PGERSRLVVL 400 IGSLGAHLHE 410 LKQRVVAEDP 420 QHFGVAVPHT 430 TRPRKSHERE 440 GVEYHFVSKQ 450 AFEADIQHNK 460 FLEHGEHKEN 470 LYGTSLEAIQ 480 TVMAKNKVCL 490 VDVEPEALRH 500 LRTPEFKPYV 510 IFVKPAIQEK 520 RKTPPVSPDS 530 EDPATPLDEQ 540 QQEMAASAAF 550 IDQHYGHLID 560 TVLVRQDLQS 570 VCSQLRAVIE 580 SLSKDTYWVP ISWVR

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005912 adherens junction
Cellular Component GO:0016324 apical plasma membrane
Cellular Component GO:0005911 cell-cell junction
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0030165 PDZ domain binding

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.