Search Results
Overview
| Uniprot ID | O95149 |
|---|---|
| Protein Name | Snurportin-1 |
| Gene Name | SNUPN |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 34 | RLSQYKSKYSSLEQS |
Function
Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs
Protein Sequence
10
MEELSQALAS
20
SFSVSQDLNS
30
TAAPHPRLSQ
40
YKSKYSSLEQ
50
SERRRRLLEL
60
QKSKRLDYVN
70
HARRLAEDDW
80
TGMESEEENK
90
KDDEEMDIDT
100
VKKLPKHYAN
110
QLMLSEWLID
120
VPSDLGQEWI
130
VVVCPVGKRA
140
LIVASRGSTS
150
AYTKSGYCVN
160
RFSSLLPGGN
170
RRNSTAKDYT
180
ILDCIYNEVN
190
QTYYVLDVMC
200
WRGHPFYDCQ
210
TDFRFYWMHS
220
KLPEEEGLGE
230
KTKLNPFKFV
240
GLKNFPCTPE
250
SLCDVLSMDF
260
PFEVDGLLFY
270
HKQTHYSPGS
280
TPLVGWLRPY
290
MVSDVLGVAV
300
PAGPLTTKPD
310
YAGHQLQQIM
320
EHKKSQKEGM
330
KEKLTHKASE
340
NGHYELEHLS
350
TPKLKGSSHS
360
PDHPGCLMEN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005643 | nuclear pore |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0061608 | nuclear import signal receptor activity |
| Molecular Function | GO:0000339 | RNA cap binding |
| Biological Process | GO:0007010 | cytoskeleton organization |
| Biological Process | GO:0051259 | protein complex oligomerization |
| Biological Process | GO:0006606 | protein import into nucleus |
| Biological Process | GO:0051262 | protein tetramerization |
| Biological Process | GO:0006404 | RNA import into nucleus |
| Biological Process | GO:0061015 | snRNA import into nucleus |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.