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Overview

Uniprot IDO95232
Protein NameLuc7-like protein 3
Gene NameLUC7L3
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
23 RNLAPDEKRSNVRWD
392 DDKKSSVKSGSREKQ

Function

Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing

Protein Sequence

10 MISAAQLLDE 20 LMGRDRNLAP 30 DEKRSNVRWD 40 HESVCKYYLC 50 GFCPAELFTN 60 TRSDLGPCEK 70 IHDENLRKQY 80 EKSSRFMKVG 90 YERDFLRYLQ 100 SLLAEVERRI 110 RRGHARLALS 120 QNQQSSGAAG 130 PTGKNEEKIQ 140 VLTDKIDVLL 150 QQIEELGSEG 160 KVEEAQGMMK 170 LVEQLKEERE 180 LLRSTTSTIE 190 SFAAQEKQME 200 VCEVCGAFLI 210 VGDAQSRVDD 220 HLMGKQHMGY 230 AKIKATVEEL 240 KEKLRKRTEE 250 PDRDERLKKE 260 KQEREEREKE 270 REREREERER 280 KRRREEEERE 290 KERARDRERR 300 KRSRSRSRHS 310 SRTSDRRCSR 320 SRDHKRSRSR 330 ERRRSRSRDR 340 RRSRSHDRSE 350 RKHRSRSRDR 360 RRSKSRDRKS 370 YKHRSKSRDR 380 EQDRKSKEKE 390 KRGSDDKKSS 400 VKSGSREKQS 410 EDTNTESKES 420 DTKNEVNGTS 430 EDIKSEGDTQ SN

Gene Ontology

Classification GO ID Description
Cellular Component GO:0016607 nuclear speck
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005685 U1 snRNP
Cellular Component GO:0071004 U2-type prespliceosome
Molecular Function GO:0003677 DNA binding
Molecular Function GO:0003729 mRNA binding
Molecular Function GO:0003723 RNA binding
Biological Process GO:0006376 mRNA splice site recognition
Biological Process GO:0008380 RNA splicing

Reference

[1] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.