Search Results
Overview
| Uniprot ID | O95235 |
|---|---|
| Protein Name | Kinesin-like protein KIF20A |
| Gene Name | KIF20A |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 453 | QNQQNRSKQNLVPFR |
| 882 | SRRSPLLKSGPFGKK |
Function
Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility
Protein Sequence
10
MSQGILSPPA
20
GLLSDDDVVV
30
SPMFESTAAD
40
LGSVVRKNLL
50
SDCSVVSTSL
60
EDKQQVPSED
70
SMEKVKVYLR
80
VRPLLPSELE
90
RQEDQGCVRI
100
ENVETLVLQA
110
PKDSFALKSN
120
ERGIGQATHR
130
FTFSQIFGPE
140
VGQASFFNLT
150
VKEMVKDVLK
160
GQNWLIYTYG
170
VTNSGKTHTI
180
QGTIKDGGIL
190
PRSLALIFNS
200
LQGQLHPTPD
210
LKPLLSNEVI
220
WLDSKQIRQE
230
EMKKLSLLNG
240
GLQEEELSTS
250
LKRSVYIESR
260
IGTSTSFDSG
270
IAGLSSISQC
280
TSSSQLDETS
290
HRWAQPDTAP
300
LPVPANIRFS
310
IWISFFEIYN
320
ELLYDLLEPP
330
SQQRKRQTLR
340
LCEDQNGNPY
350
VKDLNWIHVQ
360
DAEEAWKLLK
370
VGRKNQSFAS
380
THLNQNSSRS
390
HSIFSIRILH
400
LQGEGDIVPK
410
ISELSLCDLA
420
GSERCKDQKS
430
GERLKEAGNI
440
NTSLHTLGRC
450
IAALRQNQQN
460
RSKQNLVPFR
470
DSKLTRVFQG
480
FFTGRGRSCM
490
IVNVNPCAST
500
YDETLHVAKF
510
SAIASQLVHA
520
PPMQLGFPSL
530
HSFIKEHSLQ
540
VSPSLEKGAK
550
ADTGLDDDIE
560
NEADISMYGK
570
EELLQVVEAM
580
KTLLLKERQE
590
KLQLEMHLRD
600
EICNEMVEQM
610
QQREQWCSEH
620
LDTQKELLEE
630
MYEEKLNILK
640
ESLTSFYQEE
650
IQERDEKIEE
660
LEALLQEARQ
670
QSVAHQQSGS
680
ELALRRSQRL
690
AASASTQQLQ
700
EVKAKLQQCK
710
AELNSTTEEL
720
HKYQKMLEPP
730
PSAKPFTIDV
740
DKKLEEGQKN
750
IRLLRTELQK
760
LGESLQSAER
770
ACCHSTGAGK
780
LRQALTTCDD
790
ILIKQDQTLA
800
ELQNNMVLVK
810
LDLRKKAACI
820
AEQYHTVLKL
830
QGQVSAKKRL
840
GTNQENQQPN
850
QQPPGKKPFL
860
RNLLPRTPTC
870
QSSTDCSPYA
880
RILRSRRSPL
890
LKSGPFGKKY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0005871 | kinesin complex |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0030496 | midbody |
| Cellular Component | GO:0072686 | mitotic spindle |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005819 | spindle |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0008017 | microtubule binding |
| Molecular Function | GO:0003777 | microtubule motor activity |
| Molecular Function | GO:0019901 | protein kinase binding |
| Biological Process | GO:0001578 | microtubule bundle formation |
| Biological Process | GO:0007018 | microtubule-based movement |
| Biological Process | GO:0061952 | midbody abscission |
| Biological Process | GO:0000281 | mitotic cytokinesis |
| Biological Process | GO:0015031 | protein transport |
| Biological Process | GO:0032465 | regulation of cytokinesis |
Reference
[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.