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Overview

Uniprot IDO95236
Protein NameApolipoprotein L3
Gene NameAPOL3
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
160 LKEFPQVKRKIQESI

Function

May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles

Protein Sequence

10 MGLGQGWGWE 20 ASCFACLIRS 30 CCQVVTFTFP 40 FGFQGISQSL 50 ENVSGYYADA 60 RLEVGSTQLR 70 TAGSCSHSFK 80 RSFLEKKRFT 90 EEATKYFRER 100 VSPVHLQILL 110 TNNEAWKRFV 120 TAAELPRDEA 130 DALYEALKKL 140 RTYAAIEDEY 150 VQQKDEQFRE 160 WFLKEFPQVK 170 RKIQESIEKL 180 RALANGIEEV 190 HRGCTISNVV 200 SSSTGAASGI 210 MSLAGLVLAP 220 FTAGTSLALT 230 AAGVGLGAAS 240 AVTGITTSIV 250 EHSYTSSAEA 260 EASRLTATSI 270 DRLKVFKEVM 280 RDITPNLLSL 290 LNNYYEATQT 300 IGSEIRAIRQ 310 ARARARLPVT 320 TWRISAGSGG 330 QAERTIAGTT 340 RAVSRGARIL 350 SATTSGIFLA 360 LDVVNLVYES 370 KHLHEGAKSA 380 SAEELRRQAQ 390 ELEENLMELT 400 QIYQRLNPCH TH

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005576 extracellular region
Cellular Component GO:0016020 membrane
Molecular Function GO:0008289 lipid binding
Molecular Function GO:0005319 lipid transporter activity
Biological Process GO:0006954 inflammatory response
Biological Process GO:0042157 lipoprotein metabolic process
Biological Process GO:0043123 positive regulation of canonical NF-kappaB signal transduction

Reference

[1] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.