Search Results
Overview
| Uniprot ID | O95294 |
|---|---|
| Protein Name | RasGAP-activating-like protein 1 |
| Gene Name | RASAL1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 576 | EGYLLKRKEEPAGLA |
Function
Probable inhibitory regulator of the Ras-cyclic AMP pathway (PubMed:9751798). Plays a role in dendrite formation by melanocytes (PubMed:23999003)
Protein Sequence
10
MAKSSSLNVR
20
VVEGRALPAK
30
DVSGSSDPYC
40
LVKVDDEVVA
50
RTATVWRSLG
60
PFWGEEYTVH
70
LPLDFHQLAF
80
YVLDEDTVGH
90
DDIIGKISLS
100
REAITADPRG
110
IDSWINLSRV
120
DPDAEVQGEI
130
CLSVQMLEDG
140
QGRCLRCHVL
150
QARDLAPRDI
160
SGTSDPFARV
170
FWGSQSLETS
180
TIKKTRFPHW
190
DEVLELREMP
200
GAPSPLRVEL
210
WDWDMVGKND
220
FLGMVEFSPK
230
TLQQKPPKGW
240
FRLLPFPRAE
250
EDSGGNLGAL
260
RVKVRLIEDR
270
VLPSQCYQPL
280
MELLMESVQG
290
PAEEDTASPL
300
ALLEELTLGD
310
CRQDLATKLV
320
KLFLGRGLAG
330
RFLDYLTRRE
340
VARTMDPNTL
350
FRSNSLASKS
360
MEQFMKLVGM
370
PYLHEVLKPV
380
ISRVFEEKKY
390
MELDPCKMDL
400
GRTRRISFKG
410
ALSEEQMRET
420
SLGLLTGYLG
430
PIVDAIVGSV
440
GRCPPAMRLA
450
FKQLHRRVEE
460
RFPQAEHQDV
470
KYLAISGFLF
480
LRFFAPAILT
490
PKLFDLRDQH
500
ADPQTSRSLL
510
LLAKAVQSIG
520
NLGQQLGQGK
530
ELWMAPLHPF
540
LLQCVSRVRD
550
FLDRLVDVDG
560
DEAGVPARAL
570
FPPSAIVREG
580
YLLKRKEEPA
590
GLATRFAFKK
600
RYVWLSGETL
610
SFSKSPEWQM
620
CHSIPVSHIR
630
AVERVDEGAF
640
QLPHVMQVVT
650
QDGTGALHTT
660
YLQCKNVNEL
670
NQWLSALRKA
680
SAPNPNKLAA
690
CHPGAFRSAR
700
WTCCLQAERS
710
AAGCSRTHSA
720
VTLGDWSDPL
730
DPDAEAQTVY
740
RQLLLGRDQL
750
RLKLLEDSNM
760
DTTLEADTGA
770
CPEVLARQRA
780
ATARLLEVLA
790
DLDRAHEEFQ
800
QQERGKAALG
PLGP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0005096 | GTPase activator activity |
| Molecular Function | GO:0005543 | phospholipid binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0071277 | cellular response to calcium ion |
| Biological Process | GO:0035556 | intracellular signal transduction |
| Biological Process | GO:0046580 | negative regulation of Ras protein signal transduction |
| Biological Process | GO:1903861 | positive regulation of dendrite extension |
| Biological Process | GO:1902531 | regulation of intracellular signal transduction |
| Biological Process | GO:0007165 | signal transduction |
Reference
[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.