Search Results
Overview
| Uniprot ID | O95299 |
|---|---|
| Protein Name | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial |
| Gene Name | NDUFA10 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 181 | YNQGFIRKQCVDHYN |
| 252 | FLPEMSEKCEVLQYS |
| 80 | LAKEIAEKLGFKHFP |
Function
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Protein Sequence
10
MALRLLKLAA
20
TSASARVVAA
30
GAQRVRGIHS
40
SVQCKLRYGM
50
WHFLLGDKAS
60
KRLTERSRVI
70
TVDGNICTGK
80
GKLAKEIAEK
90
LGFKHFPEAG
100
IHYPDSTTGD
110
GKPLATDYNG
120
NCSLEKFYDD
130
PRSNDGNSYR
140
LQSWLYSSRL
150
LQYSDALEHL
160
LTTGQGVVLE
170
RSIFSDFVFL
180
EAMYNQGFIR
190
KQCVDHYNEV
200
KSVTICDYLP
210
PHLVIYIDVP
220
VPEVQRRIQK
230
KGDPHEMKIT
240
SAYLQDIENA
250
YKKTFLPEMS
260
EKCEVLQYSA
270
REAQDSKKVV
280
EDIEYLKFDK
290
GPWLKQDNRT
300
LYHLRLLVQD
310
KFEVLNYTSI
320
PIFLPEVTIG
330
AHQTDRVLHQ
340
FRELPGRKYS
350
PGYNTEVGDK
WIWLK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone |
| Biological Process | GO:0042776 | proton motive force-driven mitochondrial ATP synthesis |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0045271 | respiratory chain complex I |
| Molecular Function | GO:0008137 | NADH dehydrogenase (ubiquinone) activity |
| Biological Process | GO:0009060 | aerobic respiration |
Reference
[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.