Search Results
Overview
| Uniprot ID | O95704 |
|---|---|
| Protein Name | Amyloid-beta A4 precursor protein-binding family B member 3 |
| Gene Name | APBB3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 220 | FAFVASDKDSCMLKC |
Function
May modulate the internalization of amyloid-beta precursor protein
Protein Sequence
10
MLGKDYMLAI
20
ILVNCDDDLW
30
GDHSLEVEAG
40
LPPGWRKIHD
50
AAGTYYWHVP
60
SGSTQWQRPT
70
WELGDAEDPG
80
TGTEGIWGLR
90
PPKGRSFSSL
100
ESSLDRSNSL
110
SWYGGESYIQ
120
SMEPGAKCFA
130
VRSLGWVEVP
140
EEDLAPGKSS
150
IAVNNCIQQL
160
AQTRSRSQPP
170
DGAWGEGQNM
180
LMILKKDAMS
190
LVNPLDHSLI
200
HCQPLVHIRV
210
WGVGSSKGRD
220
RDFAFVASDK
230
DSCMLKCHVF
240
CCDVPAKAIA
250
SALHGLCAQI
260
LSERVEVSGD
270
ASCCSPDPIS
280
PEDLPRQVEL
290
LDAVSQAAQK
300
YEALYMGTLP
310
VTKAMGMDVL
320
NEAIGTLTAR
330
GDRNAWVPTM
340
LSVSDSLMTA
350
HPIQAEASTE
360
EEPLWQCPVR
370
LVTFIGVGRD
380
PHTFGLIADL
390
GRQSFQCAAF
400
WCQPHAGGLS
410
EAVQAACMVQ
420
YQKCLVASAA
430
RGKAWGAQAR
440
ARLRLKRTSS
450
MDSPGGPLPL
460
PLLKGGVGGA
470
GATPRKRGVF
480
SFLDAFRLKP
SLLHMP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0016604 | nuclear body |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0001540 | amyloid-beta binding |
| Molecular Function | GO:0050750 | low-density lipoprotein particle receptor binding |
| Molecular Function | GO:0060090 | molecular adaptor activity |
| Biological Process | GO:0050714 | positive regulation of protein secretion |
| Biological Process | GO:0006355 | regulation of DNA-templated transcription |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.