Search Results
Overview
| Uniprot ID | O95926 |
|---|---|
| Protein Name | Pre-mRNA-splicing factor SYF2 |
| Gene Name | SYF2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 63 | VEEDKRLKLPANWEA |
Function
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28076346, PubMed:28502770)
Protein Sequence
10
MAAIAASEVL
20
VDSAEEGSLA
30
AAAELAAQKR
40
EQRLRKFREL
50
HLMRNEARKL
60
NHQEVVEEDK
70
RLKLPANWEA
80
KKARLEWELK
90
EEEKKKECAA
100
RGEDYEKVKL
110
LEISAEDAER
120
WERKKKRKNP
130
DLGFSDYAAA
140
QLRQYHRLTK
150
QIKPDMETYE
160
RLREKHGEEF
170
FPTSNSLLHG
180
THVPSTEEID
190
RMVIDLEKQI
200
EKRDKYSRRR
210
PYNDDADIDY
220
INERNAKFNK
230
KAERFYGKYT
240
AEIKQNLERG
TAV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0071013 | catalytic step 2 spliceosome |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0071014 | post-mRNA release spliceosomal complex |
| Cellular Component | GO:0000974 | Prp19 complex |
| Cellular Component | GO:0071007 | U2-type catalytic step 2 spliceosome |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
| Biological Process | GO:0008284 | positive regulation of cell population proliferation |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.
[2] Chao L, Xu Y, Yang Y, Ao X, Liang J. Identification of lactylation-related biomarkers for diagnosis, prognosis, and treatment responsiveness in triple-negative breast cancer.. World J Surg Oncol 24(1):77. 2026 Jan 22. PMID: 41566505.