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Overview

Uniprot IDP00158
Protein NameCytochrome b
Gene NameMt-Cyb
OrganismMus musculus

Kla Sites from experimental identification

Position Flanking peptide
6 **MTNMRKTHPLFKI

Function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis

Protein Sequence

10 MTNMRKTHPL 20 FKIINHSFID 30 LPAPSNISSW 40 WNFGSLLGVC 50 LMVQIITGLF 60 LAMHYTSDTM 70 TAFSSVTHIC 80 RDVNYGWLIR 90 YMHANGASMF 100 FICLFLHVGR 110 GLYYGSYTFM 120 ETWNIGVLLL 130 FAVMATAFMG 140 YVLPWGQMSF 150 WGATVITNLL 160 SAIPYIGTTL 170 VEWIWGGFSV 180 DKATLTRFFA 190 FHFILPFIIA 200 ALAIVHLLFL 210 HETGSNNPTG 220 LNSDADKIPF 230 HPYYTIKDIL 240 GILIMFLILM 250 TLVLFFPDML 260 GDPDNYMPAN 270 PLNTPPHIKP 280 EWYFLFAYAI 290 LRSIPNKLGG 300 VLALILSILI 310 LALMPFLHTS 320 KQRSLMFRPI 330 TQILYWILVA 340 NLLILTWIGG 350 QPVEHPFIII 360 GQLASISYFS 370 IILILMPISG 380 IIEDKMLKLY P

Gene Ontology

Classification GO ID Description
Cellular Component GO:0016020 membrane
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0045275 respiratory chain complex III
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0016491 oxidoreductase activity
Molecular Function GO:0044877 protein-containing complex binding
Molecular Function GO:0008121 quinol-cytochrome-c reductase activity
Biological Process GO:0031100 animal organ regeneration
Biological Process GO:0045333 cellular respiration
Biological Process GO:0015990 electron transport coupled proton transport
Biological Process GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
Biological Process GO:0046686 response to cadmium ion
Biological Process GO:0051592 response to calcium ion
Biological Process GO:0033590 response to cobalamin
Biological Process GO:0046688 response to copper ion
Biological Process GO:1904421 response to D-galactosamine
Biological Process GO:0045471 response to ethanol
Biological Process GO:0033762 response to glucagon
Biological Process GO:0055093 response to hyperoxia
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0046689 response to mercury ion
Biological Process GO:0009636 response to toxic substance
Biological Process GO:0009410 response to xenobiotic stimulus

Reference

[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.