Search Results
Overview
| Uniprot ID | P00167 |
|---|---|
| Protein Name | Cytochrome b5 |
| Gene Name | CYB5A |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 19 | YTLEEIQKHNHSKST |
| 24 | IQKHNHSKSTWLILH |
| 33 | TWLILHHKVYDLTKF |
| 39 | HKVYDLTKFLEEHPG |
| 77 | TDAREMSKTFIIGEL |
Function
Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases
Protein Sequence
10
MAEQSDEAVK
20
YYTLEEIQKH
30
NHSKSTWLIL
40
HHKVYDLTKF
50
LEEHPGGEEV
60
LREQAGGDAT
70
ENFEDVGHST
80
DAREMSKTFI
90
IGELHPDDRP
100
KLNKPPETLI
110
TTIDSSSSWW
120
TNWVIPAISA
130
VAVALMYRLY
MAED
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005741 | mitochondrial outer membrane |
| Molecular Function | GO:0019899 | enzyme binding |
| Molecular Function | GO:0020037 | heme binding |
| Molecular Function | GO:0046872 | metal ion binding |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.