Search Results
Overview
| Uniprot ID | P00173 |
|---|---|
| Protein Name | Cytochrome b5 |
| Gene Name | Cyb5a |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 19 | YTLEEIQKHKDSKST |
Function
Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases. It is also involved in several steps of the sterol biosynthesis pathway, particularly in the C-6 double bond introduction during the C-6 desaturation
Protein Sequence
10
MAEQSDKDVK
20
YYTLEEIQKH
30
KDSKSTWVIL
40
HHKVYDLTKF
50
LEEHPGGEEV
60
LREQAGGDAT
70
ENFEDVGHST
80
DARELSKTYI
90
IGELHPDDRS
100
KIAKPSETLI
110
TTVESNSSWW
120
TNWVIPAISA
130
LVVALMYRLY
MAED
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0016020 | membrane |
| Molecular Function | GO:0009055 | electron transfer activity |
| Molecular Function | GO:0019899 | enzyme binding |
| Molecular Function | GO:0020037 | heme binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:0046686 | response to cadmium ion |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.