Search Results
Overview
| Uniprot ID | P00795 |
|---|---|
| Protein Name | Cathepsin D |
| Gene Name | CTSD |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 283 | TLGGKKYKLSSENYT |
| 58 | IACWIHHKYNSGKSS |
| 63 | HHKYNSGKSSTYVKN |
Function
Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation
Protein Sequence
10
GPIPEVLKNY
20
MDAQYYGEIG
30
IGTPPQCFTV
40
VFDTGSSNLW
50
VPSIHCKLLD
60
IACWIHHKYN
70
SGKSSTYVKN
80
GTTFAIHYGS
90
GSLSGYLSSQ
100
DTVSVPCNSA
110
LSGVGGIKVE
120
RQTFGEATKQ
130
PGLTFIAAKF
140
DGILGMAYPR
150
ISVNNVVPVF
160
DNLMQQKLVD
170
KDIFSFYLNR
180
DPGAQPGGEL
190
MLGGIDSKYY
200
KGSLDYHNVT
210
RKAYWQIHMN
220
QVAVGSSLTL
230
CKGGCEAIVD
240
TGTSLIVGQP
250
EEVRELGKAI
260
GAVPLIQGEY
270
MIPCEKVPSL
280
PDVTVTLGGK
290
KYKLSSENYT
300
LKVSQAGQTI
310
CLSGFMGMDI
320
PPPGGPLWIL
330
GDVFIGRYYT
340
VFDRDLNRVG
LAEAA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0005764 | lysosome |
| Cellular Component | GO:0042470 | melanosome |
| Molecular Function | GO:0004190 | aspartic-type endopeptidase activity |
| Biological Process | GO:0006508 | proteolysis |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.