Search Results
Overview
| Uniprot ID | P01041 |
|---|---|
| Protein Name | Cystatin-B |
| Gene Name | Cstb |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 30 | VKSQLEEKANQKFDV |
| 63 | KVDVGEEKCVHLRVF |
Function
This is an intracellular thiol proteinase inhibitor
Protein Sequence
10
MMCGAPSATM
20
PATTETQEIA
30
DKVKSQLEEK
40
ANQKFDVFKA
50
ISFRRQVVAG
60
TNFFIKVDVG
70
EEKCVHLRVF
80
EPLPHENKPL
90
TLSSYQTDKE
KHDELTYF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0004869 | cysteine-type endopeptidase inhibitor activity |
| Molecular Function | GO:0004866 | endopeptidase inhibitor activity |
| Molecular Function | GO:0002020 | protease binding |
| Biological Process | GO:0008344 | adult locomotory behavior |
| Biological Process | GO:1990000 | amyloid fibril formation |
| Biological Process | GO:0045861 | negative regulation of proteolysis |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.